Karl Rudolf Heinze (22 July 1865 – 26 May 1928) was a German jurist and politician.
During the Weimar Republic, as a member of the right-of-centre German People's Party (DVP) he was Vice-Chancellor of Germany and Minister of Justice in 1920/21 in the cabinet of Konstantin Fehrenbach and from 1922 to 1923 again Minister of Justice under Wilhelm Cuno.