Patrick Kombayi (2 November 1938 – 20 June 2009) was a Zimbabwean businessman, a former mayor of Gweru and an active member of the Movement for Democratic Change-Tsvangirai faction in the Midlands Province.
He served in the Senate of Zimbabwe for the Chirumhanzu-Gweru senatorial constituency.
Kombayi, a student of Robert Mugabe, was the first black train driver in Zimbabwe.
He joined Rhodesia Railways after pursuing an unsatisfying career as a schoolteacher.
Posted to Zambia, Kombayi became involved with the Zimbabwe African National Union.