Mona Octavia Musca (born Mona Octavia Nicoara; May 4, 1949) is a Romanian philologist and politician.
A former member of the National Liberal Party (PNL) and of the Liberal Democratic Party (PLD), she was a member of the Romanian Chamber of Deputies for Caras-Severin County from 1996 to 2004 and for Bucharest from 2004 to 2007.
In the Calin Popescu-Tariceanu cabinet, she served as Minister of Culture and Religious Affairs from 2004 to 2005.