Juan Bernardino Caballero de Añasco y Melgarejo (20 May 1839, Ybycuí, Paraguay – 26 February 1912, Asunción) was a Paraguayan War veteran, the President of Paraguay from 1880 until 1886 and founder of the Colorado Party.
He was the leading political figure in Paraguay from early-post-war period until the Liberal revolution of 1904.