Sergio Apostol (born January 17, 1935) is a Filipino politician.
Apostol, a Roman Catholic, graduated from the Ateneo Law School and was a member of the Ateneo Law Journal.
He passed the Philippine Bar exams in 1958, finishing 7th.
He was the City Fiscal for Quezon City, Regional Trial Court Judge, Philippine Congressman for the 2nd District of Leyte, Chairman and CEO of PNOC and Cabinet Secretary.
In 2008, Sergio Apostol was Chief Presidential Legal Counsel for Philippine President Gloria Macapagal-Arroyo.
On October 8, 2008, Eduardo Ermita confirmed Apostol's resignation, effective October 30, to prepare for his candidacy, for Leyte congressional seat, in the 2010 Philippine general election.
Apostol is a member of the board of Union Bank and the legal consultant of the SSS’ Social Security Commission (SSC).
After winning his district's seat as a Lakas-CMD party candidate of Arroyo, Apostol switched allegiance to the Liberal party of Benigno Aquino, the winner of the 2010 Presidential election.