Georges Jean Franz Köhler (April 17, 1946 in Munich – March 1, 1995 in Freiburg im Breisgau) was a German biologist.
Together with César Milstein and Niels Kaj Jerne, Köhler won the Nobel Prize in Physiology or Medicine in 1984, "for work on the immune system and the production of monoclonal antibodies".
Milstein and Köhler's technique for producing monoclonal antibodies laid the foundation for the exploitation of antibodies for diagnostics and therapeutics and many scientific applications.