Okubo Tadatomo (??? ??, December 24, 1632 – October 25, 1712) was a daimyo in early Edo period, Japan.
He was assigned by the Tokugawa shogunate to Karatsu Domain, Sakura Domain, and finally to Odawara Domain in Sagami Province, (modern-day Kanagawa Prefecture), where his descendants remained until the Meiji Restoration.