Otto Bickenbach (* 11 March 1901 in Ruppichteroth in the Rhineland, †26 November 1971 in Siegburg) was a German internist and professor at the University of Strasbourg.
He joined the Nazi Party on 1 May 1933.
Between June and August 1943 in the Natzweiler-Struthof concentration camp, Bickenbach and his assistant, Helmut Rühl, conducted a series of tests by poisonous gas in gas chamber experiments with phosgene.
More than 50 prisoners, mainly gypsies transferred for medical experiments from Auschwitz, were murdered in the course of these experiments.