Francisco Javier Santamaría (September 10, 1886 in Cacaos in Jalapa Municipality, Tabasco – March 1, 1963 in Veracruz, Veracruz) was an influential Mexican writer and politician who is best remembered for his contributions to the study of Mexican literature and lexicography; he variously worked or published as a bibliographer, essayist, geographer, journalist, judge, lawyer, lexicographer, linguist, naturalist, pedagogue, philologist, and poet.
He also served as a Senator of the Republic and as Governor of the State of Tabasco.