Anna, Princess of Mecklenburg-Schwerin (14 September 1485, Plau am See – 12 May 1525, Rödelheim) was by marriage Landgravine of Hesse.
She was a daughter of Duke Magnus II of Mecklenburg (1441–1503), and Sophie of Pomerania-Stettin (about 1460 – 1504).
She was a member of the 13th Generation of the Princely House of Mecklenburg.