Karin Wolff (born 23 February 1959 in Darmstadt) is a German politician and vice-president of Hesse.
Wolff studied history, evangelical theology and philosophy at Johannes-Gutenberg-Universität Mainz and Philipps-Universität Marburg.
She finished university and worked as a teacher in Darmstadt.
In 1976 Wolff became a member of the conservative Christian Democratic Union.
In 1995 she became a member of parliament in Hesse and became minister in Hesse on 7 April 1999.
Wolff has written two books on children and education.
She lives in Darmstadt in an openly lesbian relationship.