Edmund Lesser (12 May 1852 – 7 June 1918) was a German dermatologist who was a native of Neisse.
He studied medicine at the universities of Berlin, Bonn and Strasbourg, earning his medical doctorate in 1876.
Later he became an assistant to Oskar Simon (1845–1892) at the dermatological clinic in Breslau, and in 1882 received his habilitation at the University of Leipzig.